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Research projects in our laboratory are broadly focused on different aspects of the molecular mechanisms of defence and pathogenesis of diseases induced by virus and bacteria in plants.
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Lipids have structural and cell signaling functions. In our laboratory we study the mechanisms that coordinate the synthesis of phospholipids and their role as signal molecules during cell differentiation processes; focusing on the differentiation of neural stem cells. Knowledge of these processes is of great importance […]
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Proteins are essential for every living cell, participating in all cellular processes. The knowledge of their structure and function enables understanding the cell and living organisms’ functioning. Our group studies proteins by analyzing the relationships between their structures and functions and their possible metabolic roles in […]
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The laboratory of Physiology and Genetics of Actinomycetes carries out various lines of work related to: 1) the use of genetic engineering, metabolic engineering and synthetic biology techniques for the production of new lipidic molecules with novel physicochemical properties using Escherichia coli as a platform of […]
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The research activities carried out in our lab cover three main areas of interest: the characterization of metalo-β-lactamases(MβLs), which are zinc enzymes involved in the resistance displayed by some pathogenic bacteria to β-lactam antibiotics, the characterization of copper proteins involved in cellular respiration, and the characterization […]
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There is a demand from the population for foods of high quality in sensory characteristics, nutritional value and the absence of toxic or potentially hazardous compounds for health. Lactic acid bacteria (LAB) are the main group of microorganisms used in the production of fermented foods. The […]
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The evolution of bacterial resistance to antimicrobials poses nowadays a major thread to global human health and food security. In our group we are interested in revealing the molecular basis of the resistance mechanisms to last generation beta-lactam antibiotics, in particular the carbapenems, and the evolution […]
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Lipids are the major components of biological membranes, fulfilling structural functions, energy storage and intra-and intercellular signaling. Comprise a large group of compounds including fatty acids, sphingolipids and sterols glycerolipids, among others. Our laboratory is focused, from different perspectives, to the study of biochemistry and molecular […]
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Most bacteria detect and integrate different chemical and physical signals present in the environment to establish appropriate adaptive responses. Research carried out in our laboratory focuses on the analysis of the signaling mechanisms that modulate the expression of factors required by Salmonella enterica to stablish the infection […]
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In our group basic and applied microbiology research lines are carried out. In terms of basic research, environmental contaminant degradation pathways are studied, as well as pathways regulating the formation of bacterial biofilms and their relationship with metal oxidation. Regarding applied microbiology, the group works following […]