Tracking individual proteins on the surface of live mammalian cells reveals complex dynamics involving anomalous diffusion and clustering. Theoretical models indicate that anomalous diffusion can be caused by vastly different processes. By performing time series and ensemble analysis of extensive single-molecule tracking in combination with stochastic […]
Cells within multicellular organisms and colonies play specific, well-defined roles. This often translates into different behaviors and transcriptional programs being executed by cells located at different places of the organism. Optical microscopies are able to visualize single-cells while maintaining spatial information, and thus constitute an optimal […]
Huntington’s disease (HD) is a neurodegenerative disorder caused by the expansion of a CAG trinucleotide repeat in the first exon of the HTT gene. The resulting mutant huntingtin (mHTT) protein acquires toxic conformations and aggregates within the cells, leading to neuronal dysfunction and death. There is […]
Multidrug resistant (MDR) infections caused by the bacterial pathogen Acinetobacter baumannii (Ab) are increasing at alarming rates. Ab has become the Gram-negative bacterium with the highest rate of multidrug resistance. As such, it is categorized by the World Health Organization as a critical priority for the […]
Walter and Miriam Rutman Distinguished Professor. Department of Chemistry and Biochemistry. Worcester Polytechnic Institute. MA, USA Copper distribution networks in Pseudomonas aeruginosa El Dr José Argüello trabaja en Transportadores de metales de membranas y homoestasis de metales en bacterias. Es Rutman Distinguished Professor en Worcester Polytechnic […]
Recibiremos al Dr. Jorge Casal, quien disertará acerca de “Redes dinámicas de señalización en el ajuste de las plantas a ambientes fluctuantes”: Las plantas ajustan de manera precisa la forma y funciones de su cuerpo a las condiciones de luz y temperatura que experimentan. En cultivos, […]