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We perform molecular epidemiology studies to identify and characterize novel viruses in human and animal hosts of Argentina in accordance with the One Health guidelines, an international initiative that promotes the interdependence between human and animal health, and its link with the environment. For this, we […]
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Our laboratory has made multiple findings and developed study tools on the molecular mechanisms of signal transduction in the enterobacteria Salmonella enterica and Serratia marcescens, primary and opportunistic clinically relevant pathogens, respectively. We focus on the characterization of signal transduction systems of the two-component family (TCS), […]
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Our laboratory studies the role of fatty acid synthesis and enzyme cofactors in the cell biology and physiology of microorganisms and animals. The implications of this topic extend from the search for antimicrobials that act by interfering with fatty acid synthesis and derived metabolites, to the […]
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The research we carry out falls within a priority area: the study of antibiotic resistance mechanisms and the development of strategies to counteract them. The rapid development of antibiotic resistance represents a great challenge for the prevention and treatment of bacterial infections. It is critical to […]
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We study the three-dimensional structure of essential components of living matter in order to arrive at an atomic resolution understanding of the architecture and molecular mechanisms of life. We focus on the investigation of the molecular bases of the activity of proteins relevant to bacterial fitness, […]
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Our group studies bacterial biofilms of clinical relevance. Biofilms are communities that bacteria form on surfaces by producing an extracellular matrix (ECM) that protects and holds the cells together. Within biofilms, certain subpopulations of bacteria tolerate and survive antibiotic treatments, which seriously compromises the chances of […]
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Trypanosomatids are single-celled parasites, some of them are responsible for various diseases in humans and animals such as Trypanosoma cruzi that causes Chagas disease. According to the World Health Organization, it is one of the 17 Neglected Tropical Diseases that is endemic in Latin America. In […]